Back to: Report Your Findings

Here is the structured abstract for a systematic review that compared treatment strategies for renal artery stenosis (you might remember this topic from our intro course).

Comparative Effectiveness of Management Strategies for Renal Artery Stenosis: An Updated Systematic Review

Background:
Atherosclerotic Renal Artery Stenosis (ARAS) is associated with high blood pressure (BP), decreased kidney function, Renal Replacement Therapy (RRT), and death.

Purpose:
To compare benefits and harms of Percutaneous Transluminal Renal Angioplasty with Stent Placement (PTRAS) versus medical therapy alone in adults with ARAS.

Data Sources:
MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials from 1993 to 16 March 2016; gray literature; and prior systematic reviews.

Study Selection:
Randomized, controlled trials (RCTs); nonrandomized, comparative studies (NRCSs); single-group studies; and selected case reports that reported all-cause and cardiovascular mortality, RRT, kidney function, BP, and adverse events.

Data Extraction:
Six researchers extracted data on design, interventions, outcomes, and study quality into a web-based database.