Make your assessment: Missing Participant Data


How did you fare? For reference, here’s a chart about missing participant data that indicate a “low risk of bias” and those that indicate a“high risk of bias.”

Low risk of bias High risk of bias
No missing participant data Considerable missing participant data
It’s unlikely participants dropped out because of an effect of the treatment It’s likely participants dropped out because of an effect of the treatment
Number of missing participants and reasons for leaving are similar in both the treatment and control group Number of missing participants and reasons for leaving are very different in the treatment vs. control group
Sensitivity analysis does not change the study conclusions Sensitivity analysis does change the study conclusions
Researchers used appropriate analytic methods to adjust for missing data Researchers used no or inappropriate methods to adjust for missing data

When you’re assessing a study for attrition bias, you should look at every outcome individually to see if the missing participant data about that outcome falls in the “low risk of bias” or “high risk of bias” column. If the approach isn’t described, or you’re unsure, you should label this domain as “unclear.”

Let’s move on to our last domain: incomplete outcome reporting.